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FTDI.FT-X series USB to serial bridges can be still reasonable option even for today.
The FTDI FT260 implements entire USB protocol for human interface device (HID) class on the chip and provides USB 2.0 Full Speed (12Mbps) connectivity for broad range of peripherals communicates through I2C or UART.
FT600/601 SuperSpeed USB 3.0 to 16/32 bit FIFO interface bridge offers an alternative to Ethernet for high-speed high-volume data transfers.